Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9765Generated: October 28, 2026

Cyclopentylamine → 2-(Cyclopentylamino)-6-benzyl-7-methyl-pyrrolo[2,3-d]pyrimidine

https://huagongshe.com/reaction/9765

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentylamineHCID 2906—
Reactant2-(Methanesulfinyl)-6-benzyl-7-methyl-pyrrolo[2,3-d]pyrimidineHCID 21988361—
Product2-(Cyclopentylamino)-6-benzyl-7-methyl-pyrrolo[2,3-d]pyrimidineHCID 10308468—

Reaction Conditions

Temperature100 °C

Reaction Steps

A mixture of the sulfoxide (50 mg) from Step 3 and cyclopentylamine (1 mL) was stirred at 100° C. overnight. Excess cyclopentylamine was removed and the residue was purified by preparative TLC (25% EtOAc/hexanes) to give the desired product (26 mg). MS: 307.3 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091347B2
Source datasetuspto-grants-2006_08
ORD IDord-7df883d201ce4efdbc637fdbcca76a93
Source noteuspto-grants-2006_08