HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanol → (Benzo[b]thiophen-5-yl)-2-[(1,4-diformylpiperazin-2-yl)methoxy]ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanol | HCID 7510 | — |
| Reactant | 2-(Benzo[b]thiophen-5-yl)oxirane | HCID 15186629 | — |
| Reactant | 2-(Hydroxymethyl)piperazine-1,4-dicarbaldehyde | HCID 45099584 | — |
| Reactant | 2-(Benzo[b]furan-5-yl)oxirane | HCID 45122599 | — |
| Product | (Benzo[b]thiophen-5-yl)-2-[(1,4-diformylpiperazin-2-yl)methoxy]ethanol | HCID 53826975 | — |
Reaction Steps
The same procedure as in Production Example 43 was repeated, except that the 2-(benzo[b]furan-5-yl)oxirane and the 3-pyridinemethanol were replaced by 2-(benzo[b]thiophen-5yl)oxirane and 1,4-diformyl-2-piperazinemethanol, respecitvely, to obtain oily 1-(benzo[b]thiophen-5-yl)-2-[(1,4-diformylpiperazin-2-yl)methoxy]ethanol (compound No. 354).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05612381 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-a3271029c1064ec69595e4ad3ab6a8bb |
| Source note | uspto-grants-1997_03 |