Water → 3,8-diphenyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)pyrido[2,3-d]pyridazine

HRID 97658Notes

Reaction equation

HRID 97658 reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[Cl:30][CH2:31][c:32]1[n:33]([CH3:37])[n:34][cH:35][n:36]1.[Cs+:28].[Cs+:29].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[OH2:38].[c:1]1(-[c:7]2[cH:8][c:9]3[c:10]([c:11](-[c:15]4[cH:16][cH:17][cH:18][cH:19][cH:20]4)[n:12][n:13][cH:14]3)[nH:21][c:22]2=[O:23])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][c:9]3[c:10]([c:11](-[c:15]4[cH:16][cH:17][cH:18][cH:19][cH:20]4)[n:12][n:13][cH:14]3)[n:21][c:22]2[O:23][CH2:31][c:32]2[n:33]([CH3:37])[n:34][cH:35][n:36]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

7

Reactant 6

HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 104192195-(Chloromethyl)-1-methyl-1H-1,2,4-triazoleHCID 114834053,8-diphenyl-1H-pyrido[2,3-d]pyridazin-2-one

Product 1

HCID 99525193,8-diphenyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)pyrido[2,3-d]pyridazine

Sources & evidence

ORD record
ord-17bfea6503fc41d5bec8190b7ed2c2b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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