反应详情

2-(3-Methylphenyl)benzonitrile (18.1 moles, 3.5 g) was added slowly at -5° C. to a mixture of 10 ml nitric acid and 10 ml sulfuric acid. After 5 minutes, the reaction was diluted with cold water. The solid was collected, dissolved in THP. The solution was dried and concentrated. The solid was recrystallized from ether and hexane to yield 2.45 g of 2-(3-methyl-4-nitrophenyl)benzonitrile. (MS)

1. customThe solid was collected
2. dissolutiondissolved in THP
3. customThe solution was dried
4. concentrationconcentrated
5. customThe solid was recrystallized from ether and hexane