Nitric Acid → 2-(3-Methyl-4-nitrophenyl)benzonitrile

Participants

Reaction Steps

2-(3-Methylphenyl)benzonitrile (18.1 moles, 3.5 g) was added slowly at -5° C. to a mixture of 10 ml nitric acid and 10 ml sulfuric acid. After 5 minutes, the reaction was diluted with cold water. The solid was collected, dissolved in THP. The solution was dried and concentrated. The solid was recrystallized from ether and hexane to yield 2.45 g of 2-(3-methyl-4-nitrophenyl)benzonitrile. (MS)

Provenance & Evidence