Benzene, 1-isocyanato-4-nitro- → HCID 19967429, compound

HRID 976620Notes

Reaction equation

HRID 976620 reaction equation
[CH:1]1([NH:9][OH:10])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[N+:11]([C:14]1[CH:19]=[CH:18][C:17]([N:20]=[C:21]=[O:22])=[CH:16][CH:15]=1)([O-:13])=[O:12]>>[CH:1]1([N:9]([OH:10])[C:21]([NH:20][C:17]2[CH:16]=[CH:15][C:14]([N+:11]([O-:13])=[O:12])=[CH:19][CH:18]=2)=[O:22])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 66012Benzene, 1-isocyanato-4-nitro-HCID 18433785HCID 18433785, compound3×

Product 1

HCID 19967429HCID 19967429, compound

Procedure

Using the general method of Compound 36 Part C, cyclooctyl hydroxylamine (Compound 36 Part B, 1.0 g, 7.0 mmol) was reacted with 4-nitrophenyl isocyanate (1.2 g, 7.3 mmol) to provide 1.1 g of the desired product as a pale yellow solid, m.p. 143°-144° C. Analysis: Calculated for C15H21N3O4 : %C, 58.62; %H, 6.89: %N, 13.67; Found: %C, 58.5; %H, 7.56; %N, 13.32.

Sources & evidence

ORD record
ord-238bc46914bc469a89016920917a596c
Source dataset
uspto-grants-1997_03
Patent number
US05612377

Reaction notes

Loading…