Methylparaben → HCID 54475829, compound

HRID 976654Notes

Reaction equation

HRID 976654 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][CH:3]=1.[CH:12]1([CH2:18]Br)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1>>[CH:12]1([CH2:18][O:1][C:2]2[CH:3]=[CH:4][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:10][CH:11]=2)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 7456MethylparabenHCID 137636Cyclohexane, (bromomethyl)-

Product 1

HCID 54475829HCID 54475829, compoundYield 63.4%

Procedure

Using the general method of Compound 80 Part A, methyl 4-hydroxybenzoate (3.0 g, 19.7 mmole) was reacted with cyclohexylmethyl bromide (2.8 mL, 20.1 mmole) to provide 3.1 g of methyl 4-cyclohexylmethoxybenzoate as a white crystalline solid, m.p. 62°-63° C.

Sources & evidence

ORD record
ord-f1472762dddb4129bd78cb0ad389a4ae
Source dataset
uspto-grants-1997_03
Patent number
US05612377

Reaction notes

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