Dichloromethane → ethyl 5-[[2-(1H-imidazol-1-yl)-1-[[(4-methoxyphenyl)methoxy]methyl]ethyl]amino]-5-oxopentanoate

HRID 97667Notes

Reaction equation

HRID 97667 reaction equation
[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl:1][C:2](=[O:3])[CH2:4][CH2:5][CH2:6][C:7](=[O:8])[O:9][CH2:10][CH3:11].[Cl:38][CH2:39][Cl:40].[NH2:12][CH:13]([CH2:14][n:15]1[cH:16][n:17][cH:18][cH:19]1)[CH2:20][O:21][CH2:22][c:23]1[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]1>>[C:2](=[O:3])([CH2:4][CH2:5][CH2:6][C:7](=[O:8])[O:9][CH2:10][CH3:11])[NH:12][CH:13]([CH2:14][n:15]1[cH:16][n:17][cH:18][cH:19]1)[CH2:20][O:21][CH2:22][c:23]1[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 78881Ethyl 5-chloro-5-oxovalerateHCID 201311651-[2-amino-3-[(4-methoxyphenyl)methoxy]propyl]-1H-imidazole

Product 1

HCID 20131172ethyl 5-[[2-(1H-imidazol-1-yl)-1-[[(4-methoxyphenyl)methoxy]methyl]ethyl]amino]-5-oxopentanoate

Sources & evidence

ORD record
ord-90e44d021afe46a5a3cbf142c52d1809
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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