反应详情

1,4-Dibromobutane (81.4 mL, 0.682 mol) is added over 1 hour to a mixture of 1,2-dicarbethoxyhydrazine (100 g, 0.568 mol) and potassium carbonate (158 g, 1.14 mol) in acetonitrile (600 mL). The resultant reaction mixture is refluxed for 6 hours, cooled to room temperature, and filtered. The filtrate is concentrated in vacuo to obtain a yellow liquid which is distilled under reduced pressure to give the title product as a colorless liquid (90.8 g, bp 115°-120° C. at 0.9 mm Hg).

1. customThe resultant reaction mixture
2. temperatureis refluxed for 6 hours
3. filtrationfiltered
4. concentrationThe filtrate is concentrated in vacuo
5. customto obtain a yellow liquid which
6. distillationis distilled under reduced pressure