HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Ethyl 4-bromo-3-oxobutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Bromine | HCID 24408 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Ethyl 4-bromo-3-oxobutanoate | HCID 575284 | — |
Reaction Steps
32.5 g (0.25 mol) of ethyl acetoacetate are dissolved in 64 ml of glacial acetic acid. 40 g (0.25 mol) of bromine are added dropwise to the cooled solution. The mixture is left to stand overnight and then poured into cold water. The oil obtained is washed with water, dried and distilled in a glass filter pump vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05614351 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-ab38a895a7fc49798a9135993320f5db |
| Source note | uspto-grants-1997_03 |