Hydrochloric Acid → HCID 54080771, compound

HRID 977065Notes

Reaction equation

HRID 977065 reaction equation
[OH-].[Na+].[CH3:3][O:4][N:5]=[C:6]([C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][CH:13]=1)[C:7]([O:9]CC)=[O:8].Cl>CO>[CH3:3][O:4][N:5]=[C:6]([C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][CH:13]=1)[C:7]([OH:9])=[O:8]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 54237637HCID 54237637, compound

Product 1

HCID 54080771HCID 54080771, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

5 ml (10 mmol) of a 2N aqueous solution of sodium hydroxide were added to a solution of 1.28 g (5.07 mmol) of ethyl α-methoxyimino-4-nitrophenylacetate in methanol, and the resulting mixture was stirred overnight at room temperature. The reaction mixture was poured into 1N hydrochloric acid and extracted with ethyl acetate. The extract was dried over anhydrous magnesium sulfate and the solvent was distilled off to give 1.0 g (88% yield) of the title compound as a crude product, which was used in the following reaction without further purification.

Workup

  1. extractionextracted with ethyl acetate
  2. dry with materialThe extract was dried over anhydrous magnesium sulfate
  3. distillationthe solvent was distilled off

Sources & evidence

ORD record
ord-59e648a0f23b474ab75a66bdf7a09cd3
Source dataset
uspto-grants-1997_03
Patent number
US05614470

Reaction notes

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