HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 19965111, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 135737463 | HCID 135737463 | — |
| Product | HCID 19965111 | HCID 19965111 | 72% |
Reaction Steps
Ethyl 4-hydroxy-2-(4-isopropoxyphenyl)-5-thiazolecarboxylate prepared in Example 22 was methylated with sodium hydride and methyl iodide and hydrolyzed by a conventional process to give 2-(4-isopropoxyphenyl)-4-methoxy-5-thiazolecarboxylic acid (yield: 72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05614520 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-c59bcd9498a24a479867e0a0db354d7b |
| Source note | uspto-grants-1997_03 |