Potassium Carbonate → HCID 19965391, compound

Participants

Reaction Steps

0.55 g of benzyl 3-[4-(8-cyanoimidazo[1,2-a]pyridin-2-yl)benzamido]propionate [obtainable by reacting 4-(8-cyanoimidazo[1,2-a]pyridin-2-yl)benzoic acid with benzyl 3-aminopropionate as in Example 32] is boiled in 30 ml of methanol with 0.27 g of hydroxylamine hydrochloride in the presence of 0.72 g of K2CO3 for 4 h. After cooling, the precipitate is filtered off with suction and washed successively with water and methanol. 3-[4-(8-cyanoimidazo[1,2-a]pyridin-2-yl)benzamido]propionic acid, m.p. 212°-215°, is obtained.

Provenance & Evidence