Hydrochloric Acid → HCID 131719941, compound

Participants

Reaction Steps

0.74 g of benzyl 2-{1-[3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}acetate is stirred in 30 ml of HCl solution in ethyl acetate at room temperature. The precipitate formed is filtered off through suction, washed with a little ethyl acetate and dried. Benzyl 2-{1-[3-(4-aminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}acetate, dihydrochloride, is obtained, m.p. 224°-226°.

Provenance & Evidence