Methyl 4-Formylbenzoate → HCID 86750602, compound

HRID 977249Notes

Reaction equation

HRID 977249 reaction equation
[Cl-].[CH3:2][C:3]1[S:7][C:6]([CH2:8][P+](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=[N:5][C:4]=1[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1.[CH:34]([C:36]1[CH:45]=[CH:44][C:39]([C:40]([O:42][CH3:43])=[O:41])=[CH:38][CH:37]=1)=O>>[CH3:2][C:3]1[S:7][C:6](/[CH:8]=[CH:34]/[C:36]2[CH:45]=[CH:44][C:39]([C:40]([O:42][CH3:43])=[O:41])=[CH:38][CH:37]=2)=[N:5][C:4]=1[C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 15294Methyl 4-FormylbenzoateHCID 19965660HCID 19965660, compound

Product 1

HCID 86750602HCID 86750602, compound

Procedure

(5-Methyl-4-phenyl-2-thiazolylmethyl)triphenylphosphonium chloride and methyl 4-formylbenzoate were reacted in the same manner as in Reference Example 10 to yield methyl (E)-4-[2-(5-methyl-4-phenyl-2thiazolyl)vinyl]benzoate, which was then recrystallized from ethyl acetate to yield colorless plates having a melting point of 156°-157° C.

Sources & evidence

ORD record
ord-953a30d6df794b0ca393ede8fe92e7d0
Source dataset
uspto-grants-1997_03
Patent number
US05614544

Reaction notes

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