Hydrochloric Acid → HCID 86750620, compound

HRID 977838Notes

Reaction equation

HRID 977838 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][C@H:13]([O:21][C:22](=[O:27])[CH2:23][N:24]([CH3:26])[CH3:25])[CH2:14][CH:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)=[CH:7][C:6]=1[NH:28][C:29](=[O:45])[CH2:30][CH:31]1[C:44]2[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=2[O:38][C:37]2[C:32]1=[CH:33][CH:34]=[CH:35][CH:36]=2)([CH3:4])([CH3:3])[CH3:2].[ClH:46]>O1CCOCC1>[ClH:46].[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][C@H:13]([O:21][C:22](=[O:27])[CH2:23][N:24]([CH3:26])[CH3:25])[CH2:14][CH:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)=[CH:7][C:6]=1[NH:28][C:29](=[O:45])[CH2:30][CH:31]1[C:32]2[CH:33]=[CH:34][CH:35]=[CH:36][C:37]=2[O:38][C:39]2[C:44]1=[CH:43][CH:42]=[CH:41][CH:40]=2)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53852169HCID 53852169, compound

Product 1

HCID 86750620HCID 86750620, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Following a procedure similar to that described in Example 119, but using N,N-dimethylglycine (S)-1-(2-{4-t-butyl-3-[2-(9H-xanthen-9-yl)acetamido]phenyl}ethyl)-2-cyclohexylethyl ester (prepared as described in Example 120) and a 4N solution of hydrogen chloride in dioxane as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as a foam-like material.

Sources & evidence

ORD record
ord-ea2461acf52a40ab8be1e8a68fd46bfe
Source dataset
uspto-grants-1997_03
Patent number
US05614550

Reaction notes

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