HRID977889

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID19966080

1-(Phenylmethyl) 4-carboxybenzeneacetate

C16H14O4

结构：CC(C)(C)c1ccc(CCC(O)CC2CCCCC2)cc1NC(=O)CC1c2ccccc2Oc2ccccc21

HCID19966195

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1ccc(CCC(CC2CCCCC2)OC(=O)c2ccc(CC(=O)OCc3ccccc3)cc2)cc1NC(=O)CC1c2ccccc2Oc2ccccc21

HCID19966156

未命名化合物

PROCEDURE

实验过程

Following a procedure similar to that described in Preparation 25, but using benzyl 4-carboxyphenylacetate [prepared as described in step (iv) above] and N-[2-t-butyl-5-(4-cyclohexyl-3-hydroxybutyl)phenyl]-2-(9H-xanthen-9-yl)acetamide (prepared as described in Example 12) as starting materials, in relative proportions similar to those used in that Preparation, the title compound was obtained as a foam-like material.

WORKUP

后处理

customthat described in Preparation 25
customin relative proportions similar to those used in that Preparation

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-27cf3ecbe07b4b4992680acbdba80d7c
来源数据集: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05614550
来源说明: uspto-grants-1997_03

反应 SMILES

[C:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:12])=[CH:6][CH:5]=1)([OH:3])=[O:2].[C:21]([C:25]1[CH:30]=[CH:29][C:28]([CH2:31][CH2:32][CH:33](O)[CH2:34][CH:35]2[CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]2)=[CH:27][C:26]=1[NH:42][C:43](=[O:59])[CH2:44][CH:45]1[C:58]2[CH:57]=[CH:56][CH:55]=[CH:54][C:53]=2[O:52][C:51]2[C:46]1=[CH:47][CH:48]=[CH:49][CH:50]=2)([CH3:24])([CH3:23])[CH3:22]>>[C:21]([C:25]1[CH:30]=[CH:29][C:28]([CH2:31][CH2:32][CH:33]([O:2][C:1](=[O:3])[C:4]2[CH:5]=[CH:6][C:7]([CH2:10][C:11]([O:13][CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[O:12])=[CH:8][CH:9]=2)[CH2:34][CH:35]2[CH2:36][CH2:37][CH2:38][CH2:39][CH2:40]2)=[CH:27][C:26]=1[NH:42][C:43](=[O:59])[CH2:44][CH:45]1[C:58]2[CH:57]=[CH:56][CH:55]=[CH:54][C:53]=2[O:52][C:51]2[C:46]1=[CH:47][CH:48]=[CH:49][CH:50]=2)([CH3:24])([CH3:22])[CH3:23]