Nitric Acid → 1,3-dimethyl-4-nitro-1H-pyrazole-5-carboxylic acid

Participants

Reaction Steps

One-hundred and twelve grams concentrated sulfuric acid is added to 42 ml 90% nitric acid at 70°-80° C. To this 39 grams 1,3-dimethylpyrazole-5-carboxylic acid is added in portions over one hour such that temperature does not go over 90° C. After 2.5 hours the reaction mixture was cooled and poured over ice. The resulting percipitate was filtered, dried, and recrystallized in ethanol, to produce 1,3-dimethyl-4-nitropyrazol-5-carboxylic acid having mp 141°-142° C.

Provenance & Evidence