Iodoethane → Ethyl 1-benzyl-5-(1,3-dithiol-2-ylidene)-3-ethyl-4,6-dioxopiperidine-3-carboxylate

HRID 977958Notes

Reaction equation

HRID 977958 reaction equation
[CH2:1]([N:8]1[C:13](=[O:14])[C:12](=[C:15]2[S:19][CH:18]=[CH:17][S:16]2)[C:11](=[O:20])[CH:10]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:26](I)[CH3:27]>>[CH2:1]([N:8]1[C:13](=[O:14])[C:12](=[C:15]2[S:16][CH:17]=[CH:18][S:19]2)[C:11](=[O:20])[C:10]([CH2:26][CH3:27])([C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 13934862Ethyl 1-benzyl-5-(1,3-dithiol-2-ylidene)-4,6-dioxopiperidine-3-carboxylate

Product 1

HCID 20204024Ethyl 1-benzyl-5-(1,3-dithiol-2-ylidene)-3-ethyl-4,6-dioxopiperidine-3-carboxylateYield 79.3%

Procedure

Ethyl 1-benzyl-5-(1,3-dithiol-2-ylidene)-4.6-dioxopiperidine-3-carboxylate (2.70 g) and ethyl iodide (0.71 ml) are treated in the same manner as described in Example 25-(1), whereby ethyl 1-benzyl-5-(1,3-dithiol-2-ylidene)-3-ethyl-4,6-dioxopiperidine-3-carboxylate (2.30 g, 79.3%) is obtained as pale yellow oil.

Sources & evidence

ORD record
ord-af3453761802444ebbbce2f847c482f8
Source dataset
uspto-grants-1987_05
Patent number
US04663319

Reaction notes

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