Acryloyl chloride → HCID 19826117, compound

HRID 978000Notes

Reaction equation

HRID 978000 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][NH:8][CH2:9][CH3:10])=[CH:3][CH:2]=1.[C:11](Cl)(=[O:14])[CH:12]=[CH2:13]>C(N(CC)CC)C>[CH2:9]([N:8]([CH2:7][C:4]1[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=1)[C:11](=[O:14])[CH:12]=[CH2:13])[CH3:10]

Participants

4

Reactant 2

HCID 13140Acryloyl chlorideHCID 96681N-Ethylpyridine-4-methylamine

Product 1

HCID 19826117HCID 19826117, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Following the method of Example 3, 4-picolyl-ethylamine (4.27 g, 0.035 mole) was reacted with acryloyl chloride (3.15 g, 0.035 mole) was triethylamine (21 ml) and purified by chromatography on silica.

Workup

  1. custompurified by chromatography on silica

Sources & evidence

ORD record
ord-d11255fb17e042c1bc9e605e9c18ced8
Source dataset
uspto-grants-1987_05
Patent number
US04663333

Reaction notes

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