反应详情

温度

-5 °C

The title compound of Example 15 (32.2 g, 0.106 mole) and water (1.9 ml) were dissolved in acetone (150 ml) with stirring and cooled to -5° C. Triethylphosphine (15.7 ml, 0.106 mole) was added dropwise over a period of 40 minutes. The reaction was stirred at 0° C. for 1 hour and then at room temperature for 2 hours. The solvent was evaporated and the product isolated by chromatography on silica.

1. stirringThe reaction was stirred at 0° C. for 1 hour
2. customThe solvent was evaporated
3. customthe product isolated by chromatography on silica