HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → Ethyl (2-acetyl-3-hydroxyphenoxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2',6'-Dihydroxyacetophenone | HCID 69687 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Ethyl (2-acetyl-3-hydroxyphenoxy)acetate | HCID 4673143 | — |
Reaction Steps
A mixture of 2,6-dihydroxyacetophenone (40 g), ethyl bromoacetate (48 g) and potassium carbonate (58 g) in acetone (500 ml) was refluxed for 3 hours. The mixture was cooled and filtered. The solution was evaporated to dryness and the crude solid extracted with boiling hexane. Upon cooling, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04663347 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-5daafc56e4054350848aa44c9f5eec5d |
| Source note | uspto-grants-1987_05 |