反应详情

A mixture of 2,6-dihydroxyacetophenone (40 g), ethyl bromoacetate (48 g) and potassium carbonate (58 g) in acetone (500 ml) was refluxed for 3 hours. The mixture was cooled and filtered. The solution was evaporated to dryness and the crude solid extracted with boiling hexane. Upon cooling, the title compound was obtained.

1. temperaturewas refluxed for 3 hours
2. temperatureThe mixture was cooled
3. filtrationfiltered
4. customThe solution was evaporated to dryness
5. extractionthe crude solid extracted with boiling hexane
6. temperatureUpon cooling