beta-Cyclodextrin → HCID 54342440, compound

HRID 978242Notes

Reaction equation

HRID 978242 reaction equation
C(O)[C@H]1[O:7][C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]8[C@H](O)[C@@H](O)[C@@H](O[C@H]1[C@H](O)[C@H]2O)O[C@@H]8CO)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)O[C@@H]3CO.[OH:78][C:79]1[CH:84]=[C:83](O)[C:82]([C:86]([OH:88])=[O:87])=[CH:81][C:80]=1[CH:89]=[CH:90][C:91]([C:93]1[CH:98]=[CH:97][CH:96]=[CH:95][CH:94]=1)=[O:92]>C(O)[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]1[C@H](O)[C@H]2O)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)O[C@@H]3CO>[OH:78][C:79]1[CH:84]=[CH:83][C:82]([C:86]([OH:88])=[O:87])=[CH:81][C:80]=1[CH:89]=[CH:90][C:91]([C:93]1[CH:98]=[CH:97][C:96]([OH:7])=[CH:95][CH:94]=1)=[O:92]

Participants

4

Reactant 2

HCID 444041beta-CyclodextrinHCID 536874522,4-Dihydroxy-5-(3-oxo-3-phenylprop-1-en-1-yl)benzoic acid

Product 1

HCID 54342440HCID 54342440, compound

Reagents, catalysts & solvents 1

HCID 444913Alpha-CyclodextrinCatalyst

Procedure

2,4'-Dihydroxy-5-carboxychalcone is prepared in substantially the same manner as in Example 8, except that 4.5 g of the fixed α-cyclodextrin prepared in Example 10 is used as a catalyst instead of the fixed β-cyclodextrin. The recovery of the catalyst, the yield of and the selectivity for 2,4-dihydroxy-5-carboxychalcone are 100%, 53% on molar basis and 93%, respectively.

Sources & evidence

ORD record
ord-59b37acf4f1f44198dd8a6304be12d92
Source dataset
uspto-grants-1987_05
Patent number
US04663478

Reaction notes

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