Phenylhydrazine → ST50547281

HRID 978331Notes

Reaction equation

HRID 978331 reaction equation
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:9][N:10]=[C:11]=[S:12]>C1C=CC=CC=1>[CH3:9][NH:10][C:11](=[S:12])[NH:8][NH:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 7516PhenylhydrazineHCID 11167Methyl isothiocyanate

Product 1

HCID 4405145ST50547281Yield 67.4%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

In 500 ml of benzene was dissolved 108 g of phenylhydrazine, and 73 g of methyl isothiocyanate was added dropwise to the solution, followed by heat refluxing. As the reaction proceeded, crystals were preicpitated. The thus formed crystals were filtered and dried to obtain 122 g of 4-methyl-1-phenylthiosemicarbazide.

Workup

  1. additionwas added dropwise to the solution
  2. temperatureby heat
  3. temperaturerefluxing
  4. filtrationThe thus formed crystals were filtered
  5. customdried

Sources & evidence

ORD record
ord-3f553722414249b2aa8eb0457b8cc2a3
Source dataset
uspto-grants-1987_05
Patent number
US04665017

Reaction notes

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