Butyric Acid → Butyric anhydride

HRID 978350Notes

Reaction equation

[C:1]([OH:6])(=[O:5])[CH2:2][CH2:3][CH3:4].[C:7](Cl)(=[O:11])[CH2:8][CH2:9][CH3:10]>>[C:1]([O:6][C:7](=[O:11])[CH2:8][CH2:9][CH3:10])(=[O:5])[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 264Butyric Acid

HCID 8855Butyryl chloride

Product 1

HCID 7798Butyric anhydride

Procedure

Molar quantities of butyric acid and butyryl chloride are heated together on a water-bath for 1 hour and then boiled for 7 hours in an oil-bath. Butyric anhydride, b.p. 198°-199° C./765 mm, is obtained on distillation of the resulting mixture.

Sources & evidence

ORD record: ord-5cfac100d0ef48fdbd4bfd11c83989fd
Source dataset: uspto-grants-1987_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04665070

Reaction notes

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