Hydrochloric Acid → HCID 20139188, compound

HRID 978361Notes

Reaction equation

HRID 978361 reaction equation
[ClH:1].[NH2:2][C:3]1[CH:16]=[CH:15][C:6]2[C:7](=[O:14])[O:8][C:9]([O:11][CH2:12][CH3:13])=[N:10][C:5]=2[CH:4]=1.C(OCC)C>O1CCOCC1>[ClH:1].[NH2:2][C:3]1[CH:16]=[CH:15][C:6]2[C:7](=[O:14])[O:8][C:9]([O:11][CH2:12][CH3:13])=[N:10][C:5]=2[CH:4]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 13827094HCID 13827094, compound

Product 1

HCID 20139188HCID 20139188, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

A stoichiometric amount of 3% hydrogen chloride in dioxane is added to a solution of 1.0 g. of 7-amino-2-ethoxy-4H-3,1-benzoxazin-4-one in 20 ml dioxane. Diethyl ether is added until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized to give 7-amino-2-ethoxy-4H-3,1-benzoxazin-4-one hydrochloride.

Workup

  1. filtrationThe product is filtered
  2. washwashed with ether, air
  3. customdried
  4. customrecrystallized

Sources & evidence

ORD record
ord-c5f31054a4874b12b346c8b08bf97d4c
Source dataset
uspto-grants-1987_05
Patent number
US04665070

Reaction notes

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