反应详情

Two moles 4-amino-m-cresol and 1 mole 2-chloromethyl-2-imidazoline hydrochloride are refluxed for 3 hours, within absolute ethanol. After cooling, the insoluble fraction is suction filtered and the ethanol solution is evaporated in vacuo. The evaporation residue is recrystallized from methanol:diethyl ether; M.p.=205°-207° C.

1. temperatureAfter cooling
2. filtrationfiltered
3. customthe ethanol solution is evaporated in vacuo
4. customThe evaporation residue is recrystallized from methanol