Sodium ion → N-[5-chloro-7-(3-ethoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Reaction equation
[CH3:41][Si:42]([N-:43][Si:44]([CH3:45])([CH3:46])[CH3:47])([CH3:48])[CH3:49].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12.[Cl:24][c:25]1[c:26]([NH2:40])[c:27]2[c:28]([c:32]([C:34]#[C:35][CH2:36][O:37][CH2:38][CH3:39])[cH:33]1)[O:29][CH2:30][O:31]2.[Na+:50].[O:51]=[CH:52][N:53]([CH3:54])[CH3:55]>>[c:2]1([NH:40][c:26]2[c:25]([Cl:24])[cH:33][c:32]([C:34]#[C:35][CH2:36][O:37][CH2:38][CH3:39])[c:28]3[c:27]2[O:31][CH2:30][O:29]3)[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-392343897f7544c6984ad5b4f6cb4e1a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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