1,2-Dichloroethane → tert-butyl 4-(((2,5-dimethyl-1H-imidazol-4-yl)methyl)amino)-1-piperidinecarboxylate

HRID 97853Notes

Reaction equation

HRID 97853 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH2:14])[CH2:12][CH2:13]1.[C:24]([O:25][BH-:26]([O:27][C:28](=[O:29])[CH3:30])[O:31][C:32](=[O:33])[CH3:34])(=[O:35])[CH3:36].[C:38](=[O:39])([O-:40])[O-:41].[CH3:15][c:16]1[nH:17][c:18]([CH3:23])[c:19]([CH:21]=[O:22])[n:20]1.[CH3:48][C:49](=[O:50])[OH:51].[Cl:44][CH2:45][CH2:46][Cl:47].[K+:42].[K+:43].[Na+:37]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:21][c:19]2[c:18]([CH3:23])[nH:17][c:16]([CH3:15])[n:20]2)[CH2:12][CH2:13]1

Participants

9

Reactant 8

HCID 111,2-DichloroethaneHCID 176Acetic AcidHCID 813Potassium Cation2×HCID 923Sodium ionHCID 19660Carbonate IonHCID 12682914-Amino-1-Boc-piperidineHCID 2724942TriacetoxyborohydrideHCID 132064322,5-Dimethyl-1H-imidazole-4-carbaldehyde

Product 1

HCID 23138170tert-butyl 4-(((2,5-dimethyl-1H-imidazol-4-yl)methyl)amino)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-59a1b87b41e04d6d8a23a795ed843370
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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