Dihydrofolic Acid → Tetrahydrofolic acid

Participants

Reaction Steps

Then, 0.112 g of a 5% platinum-activated carbon catalyst (containing the noble metal in an amount of 0.26% by weight based on the dihydrofolic acid) was added to the flask, and hydrogenation was carried out in the same manner as described in Example 1 to obtain 1.439 g (65.7% yield) of tetrahydrofolic acid.

Provenance & Evidence