Ethylenediamine → HCID 20203460, compound

HRID 978633Notes

Reaction equation

HRID 978633 reaction equation
Cl[C:2]1[C:3]([S:14]([CH2:17][CH2:18][C:19]([OH:21])=[O:20])(=[O:16])=[O:15])=[CH:4][C:5]([N+:11]([O-:13])=[O:12])([N+]([O-])=O)[CH2:6][CH:7]=1.[NH2:22][CH2:23][CH2:24][NH2:25]>C(O)(C)C>[NH2:22][CH2:23][CH2:24][NH:25][C:2]1[CH:7]=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][C:3]=1[S:14]([CH2:17][CH2:18][C:19]([OH:21])=[O:20])(=[O:16])=[O:15]

Participants

4

Reactant 2

HCID 3301EthylenediamineHCID 86741492HCID 86741492, compound

Product 1

HCID 20203460HCID 20203460, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Conditions

Temperature
0 °C

Procedure

29.5 g of 3-(2-chloro-5-nitro-5-nitrophenylsulphonyl)propionic acid and 15 g of 1,2-diaminoethane are refluxed in 150 ml of isopropanol for two hours. The reaction mixture is cooled down to 0° C. and filtered with suction. The isolation is suspended in 100 ml of water, the suspension is brought to pH 3.5, and 15 g of sodium chloride are added for salting out. The precipitated betaine is filtered off with suction and dried. The yield of 3-[2-(-aminoethyl)amino-5-nitrophenylsulphonyl]-propionic acid is 28.5 g.

Workup

  1. filtrationfiltered with suction
  2. additionare added
  3. filtrationThe precipitated betaine is filtered off with suction
  4. customdried

Sources & evidence

ORD record
ord-6a57b54a4f094365987ddf3a23888109
Source dataset
uspto-grants-1987_05
Patent number
US04665179

Reaction notes

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