Ethanol → HCID 13393807, compound

HRID 978777Notes

Reaction equation

HRID 978777 reaction equation
[Na].[CH2:2]([OH:4])[CH3:3].Cl[C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[O:9][CH:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:7]=1[CH:22]=[O:23]>O>[CH2:2]([O:4][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[O:9][CH:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:7]=1[CH:22]=[O:23])[CH3:3]

Participants

5

Reactant 3

HCID 702EthanolHCID 5360545Sodium2×HCID 13393783HCID 13393783, compound

Product 1

HCID 13393807HCID 13393807, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
40 °C

Procedure

1.7 g sodium is allowed to react with 150 ml absolute ethanol. After complete disappearance of sodium, one adds 13.5 g 4-chloro-3-formyl-flav-3-ene. After stirring 30 minutes at 40° C., 300 ml of water is added and a precipitate is formed, filtered, washed with water and dried. The solid is crystallized in hexane. Pure 4-ethoxy-3-formyl-flav-3-ene is obtained as yellow crystals; m.p. 80°-82° C.

Workup

  1. customa precipitate is formed
  2. filtrationfiltered
  3. washwashed with water
  4. customdried
  5. customThe solid is crystallized in hexane

Sources & evidence

ORD record
ord-9c06ec58f4f845fb9b02df1263fb1fb6
Source dataset
uspto-grants-1987_05
Patent number
US04665202

Reaction notes

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