反应详情

温度

60 °C

736 g of tertiarybutylamine and 500 g of 2-chloroethoxyethanol were placed in 2 liters of ethanol and heated at 60° C. overnight. The temperature was then gradually raised to 80° C. and held for 5 days. The reaction mixture was cooled to 50° C. and then treated with 247 g of KOH. After 1 hour at refluxing the reaction was cooled, filtered, vacuum stripped and distilled. The yield of the distilled product, which calculates as a 75.6% yield, was 491 g, and it had a b.p. of 117° C. at 10 mm. Analysis calculated for C8H19NO2 : % C 59.63; %H, 11.80, %N, 8.70; Found: % C, 58.99, %H, 11.82; %N, 8.38.

1. temperatureThe temperature was then gradually raised to 80° C.
2. temperatureThe reaction mixture was cooled to 50° C.
3. temperatureAfter 1 hour at refluxing the reaction
4. temperaturewas cooled
5. filtrationfiltered
6. distillationdistilled