HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Benzenamine, 4-chloro-N-(4-nitrophenyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Benzenamine, 4-chloro-N-(4-nitrophenyl)- | HCID 155617 | — |
| Solvent | 4-Nitrophenol | HCID 980 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Nitrobenzene | HCID 7416 | — |
| Solvent | 1-Iodopropane | HCID 33643 | — |
| Product | Benzenamine, 4-chloro-N-(4-nitrophenyl)- | HCID 155617 | — |
| Product | HCID 20159089 | HCID 20159089 | — |
Reaction Steps
The starting aniline was obtained from the corresponding nitro compound by reduction with hydrogen under the influence of Raney nickel as a catalyst; a mixture of equal parts by volume of ethanol and ethyl acetate was used as a solvent. 1-Nitro-4-[N-(4-chlorophenyl)-N-propylamino]benzene was prepared by an alkylation of 1-nitro-4-(4-chloroanilino)benzene with propyliodide in dimethylformamide as a solvent under the influence of KOH. 1-Nitro-4-(4-chloroanilino)benzene was formed by a coupling at high temperature of p-chlorobenzeneisocyanate and p-nitrophenol in nitrobenzene as a solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04665235 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-05f37c1ee26043ddaa68e9b960df0bc7 |
| Source note | uspto-grants-1987_05 |