HCID 20201103, compound → 4-Methyl-2-(methylsulfanyl)thiophen-3-amine

HRID 978924Notes

Reaction equation

HRID 978924 reaction equation
[CH3:1][S:2][C:3]1[S:4][CH:5]=[C:6]([CH3:11])[C:7]=1[N+:8]([O-])=O>C(OCC)C>[CH3:1][S:2][C:3]1[S:4][CH:5]=[C:6]([CH3:11])[C:7]=1[NH2:8]

Participants

3

Reactant 1

HCID 20201103HCID 20201103, compound

Product 1

HCID 202011094-Methyl-2-(methylsulfanyl)thiophen-3-amine

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

6 g (0.22 gram atoms) freshly prepared aluminium amalgam are added over a period of about two minutes to 18.9 g (0.1 mol) of 2-methylthio-4-methyl-3-nitrothiophene dissolved in 200 ml of moist diethylether. The vigorous reaction which sets in after 5-10 minutes is kept under control by cooling the flask in ice.

Workup

  1. customThe vigorous reaction which
  2. customafter 5-10 minutes
  3. temperatureby cooling the flask in ice

Sources & evidence

ORD record
ord-dfa6b5a73c394992a319395e4b4c1656
Source dataset
uspto-grants-1987_05
Patent number
US04666502

Reaction notes

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