HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-[(2,4-Dimethylthiophen-3-yl)amino]-2-oxoethyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Acetoxyacetyl chloride | HCID 26297 | — |
| Reactant | 2,4-Dimethylthiophen-3-amine | HCID 13341198 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-[(2,4-Dimethylthiophen-3-yl)amino]-2-oxoethyl acetate | HCID 20201087 | — |
Reaction Steps
To 12.7 g (0.1 mol) of 2,4-dimethyl-3-aminothiophene, 13.8 g (0.1 mol) of K2CO3, 20 ml of water and 150 ml of methylene chloride are added dropwise at ambient temperature 15 g (0.11 mol) of acetoxyacetyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04666502 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-da3227bced5c4028b9f8fb31f17761ae |
| Source note | uspto-grants-1987_05 |