Water → HCID 13491961, compound

Participants

Reaction Steps

To a suspension of 2.1 g (0.007 mol) of 1,6-bis(3-amino-4-hydroxyphenyl)hexane in 10 ml of isobutyl methyl ketone was added 3.0 g (0.0357 mole) of sodium bicarbonate and 10 ml of water. The suspension was stirred in an ice bath and 1.9 g (0.016 mole) of chloroacetyl chloride was added dropwise. The reaction was carried out in a manner similar to that in Example 23 to yield 1.0 g of product of m.p. 219°-225° C.

Provenance & Evidence