Isobutyraldehyde → HCID 53802668, compound

Participants

Reaction Steps

19.7 g (0.1 mol) of 3-hydrazino-2H,3H-1,2-benzisothiazole 1,1-dioxide are dissolved in 200 ml of dioxane at 40°-50° C., and 8 g (0.11 mol) of isobutyraldehyde are added dropwise to the thoroughly stirred mixture. The product is precipitated directly during this procedure. When the addition is complete, the mixture is heated to 80°-90° C. for about 20 minutes and then cooled, and the crystals are filtered off under suction. 22.1 g (88.1% of theory) of 3-isobutylidenehydrazino-1,2-benzisothiazole 1,1-dioxide of melting point 225° C. are obtained in this manner.

Provenance & Evidence