Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dichloromaleic anhydride | HCID 70728 | — |
| Reactant | 3-(4-Chlorophenyl)propan-1-amine | HCID 6485772 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178525580 | HCID 178525580 | 82% |
Reaction Steps
16.7 g (0.1 mol) of dichloromaleic anhydride and 17.0 g (0.1 mol) of 3-(4-chlorophenyl)-propylamine are stirred in 100 ml of glacial acetic acid under reflux for 4 hours. 50 ml of water are added and the mixture is cooled to 20° C. The product is filtered off with suction and dried. 26.1 g (82% of theory) of dichloromaleic acid N-[3-(4-chlorophenyl)-propyl]-imide of melting point 72°-73° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04666935 |
|---|
| Source dataset | uspto-grants-1987_05 |
|---|
| ORD ID | ord-0f3efac96b3d445791bbd1d9a2893ed7 |
|---|
| Source note | uspto-grants-1987_05 |
|---|
