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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 97935Generated: October 27, 2026

1-Methoxy-2-propanol → 4-Hydroxy-4-(4-{7-[2-(methanesulfonyl-methyl-amino)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino}-3-methoxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/97935

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methoxy-2-propanolHCID 7900—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-(4-Amino-3-methoxy-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl esterHCID 66710949—
ReactantTrifluoro-methanesulfonic acid 7-[2-(methanesulfonyl-methyl-amino)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-yl esterHCID 86661681—
Product4-Hydroxy-4-(4-{7-[2-(methanesulfonyl-methyl-amino)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino}-3-methoxy-phenyl)-piperidine-1-carboxylic acid tert-butyl esterHCID 66711492—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-24a738c3bb904d61bdef7f920a3216d0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)