1-Methoxy-2-propanol → 4-Hydroxy-4-(4-{7-[2-(methanesulfonyl-methyl-amino)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino}-3-methoxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([c:15]2[cH:16][c:17]([O:22][CH3:23])[c:18]([NH2:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH3:24][S:25](=[O:26])(=[O:27])[N:28]([c:29]1[c:30](-[c:35]2[cH:36][cH:37][c:38]3[cH:39][n:40][c:41]([O:44][S:45]([C:46]([F:47])([F:48])[F:49])(=[O:50])=[O:51])[n:42][n:43]23)[cH:31][cH:32][cH:33][cH:34]1)[CH3:52].[CH3:62][O:63][CH2:64][CH:65]([OH:66])[CH3:67].[CH:53]([N:54]([CH2:55][CH3:56])[CH:57]([CH3:58])[CH3:59])([CH3:60])[CH3:61]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([c:15]2[cH:16][c:17]([O:22][CH3:23])[c:18]([NH:21][c:41]3[n:40][cH:39][c:38]4[cH:37][cH:36][c:35](-[c:30]5[c:29]([N:28]([S:25]([CH3:24])(=[O:26])=[O:27])[CH3:52])[cH:34][cH:33][cH:32][cH:31]5)[n:43]4[n:42]3)[cH:19][cH:20]2)[CH2:12][CH2:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-24a738c3bb904d61bdef7f920a3216d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…