HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-Chloroethane → HCID 16109514, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2,3-Dihydro-2,2-dimethyl-7-benzofuranol | HCID 15278 | — |
| Catalyst | Trioctylmethylammonium chloride | HCID 21218 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 16109514 | HCID 16109514 | — |
Reaction Steps
To 200 ml. methylene-chloride 32.84 g. (0.2 mole) 2,3-dihydro-2,2-dimethyl-7-hydroxy-benzofuran, 57.37 g. (0.4 mole) 1-bromo-2-chloro-ethane 200 ml. 2N sodium hydroxide solution and 8 g. Adogen 464 phase transfer catalyst (tri-C8-10 -alkyl-methyl-ammonium-chloride) are added. The reaction mixture is heated under vigorous stirring for 7 hours and the reaction is monitored by gas chromatographic analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04668274 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-53dbd3f7219e4ebe9551f473c41a6134 |
| Source note | uspto-grants-1987_05 |