HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 15692309, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 1-[Bis(hydroxymethyl)-methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline | HCID 13696680 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 15692309 | HCID 15692309 | 71% |
Reaction Steps
0.03 mole (7.96 g) of 1-[bis(hydroxymethyl)-methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline is dissolved in 40 ml of absolute ethanol. 0.045 mole (6.39 g) of methyl iodide is added to the solution and the reaction mixture is kept at 30° to 40° C. for 6 hours. The precipitated crystals are filtered off and recrystallized from ethanol. The aimed compound is obtained with a melting point of 189° to 193° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04668688 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-ab34157409794e6996a4e6b9bc123207 |
| Source note | uspto-grants-1987_05 |