HCID 13922926, compound → HCID 178448724, compound

Participants

Reaction Steps

A mixture of 1-(2-cyano-3,4-dimethoxyphenyl)-3-butyl urea (5.2 g, 18.8 mmol) in 50 ml of 0.5N methanolic sodium methoxide was heated at reflux under nitrogen for 18 hours. The reaction solution was cooled and a precipitate which formed was collected, washed with cold methanol and dried giving 3.61 g (68.4%) of analytical product, mp 165°-168°.

Provenance & Evidence