Glycine → N-(1-Oxodecyl)glycine

HRID 979748Notes

Reaction equation

HRID 979748 reaction equation
[C:1]([Cl:12])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[NH2:13][CH2:14][C:15]([OH:17])=[O:16]>>[C:1]([Cl:12])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[NH2:13][CH2:14][C:15]([OH:17])=[O:16].[C:1]([NH:13][CH2:14][C:15]([OH:17])=[O:16])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

5

Reactant 2

HCID 750GlycineHCID 66982Decanoyl chloride

Product 3

HCID 750GlycineHCID 66982Decanoyl chlorideHCID 1712391N-(1-Oxodecyl)glycineYield 94%

Procedure

N-Decanoylglycine was prepared by reaction of decanoyl chloride with glycine according to the procedure described in Example I. From 47.7 g (0.25 mol) of decanoyl chloride and 18.8 g (0.25 mol) of glycine was obtained 54.1 g (94%) of N-decanoylglycine, mp 104°-108° C.

Sources & evidence

ORD record
ord-0eb27852a82d4d72adeebc6964bdc46c
Source dataset
uspto-grants-1987_01
Patent number
US04634551

Reaction notes

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