Hydrochloric Acid → HCID 70473998, compound

HRID 979960Notes

Reaction equation

HRID 979960 reaction equation
[C:1]([O:5][C:6](=[O:31])[C@@H:7]1[CH2:11][CH2:10][CH2:9][N:8]1[C:12](=[O:30])[N:13]([CH3:29])[NH:14][CH:15]([C:24]([O:26][CH2:27][CH3:28])=[O:25])[CH2:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)(C)(C)[CH3:2].[ClH:32]>C(O)C>[ClH:32].[CH2:1]([O:5][C:6](=[O:31])[C@@H:7]1[CH2:11][CH2:10][CH2:9][N:8]1[C:12](=[O:30])[N:13]([CH3:29])[NH:14][CH:15]([C:24]([O:26][CH2:27][CH3:28])=[O:25])[CH2:16][CH2:17][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 18606052HCID 18606052, compound

Product 1

HCID 70473998HCID 70473998, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

An ice-cold solution of N-(1-carboethoxy-3-phenylpropyl)-α-azaalanyl-(L)-proline t-butyl ester (16S) in absolute ethanol was saturated with hydrogen chloride. After one hour, the solution was evaporated to dryness and the product purified by chromatography on LH-20 (in methanol).

Workup

  1. customthe solution was evaporated to dryness
  2. customthe product purified by chromatography on LH-20 (in methanol)

Sources & evidence

ORD record
ord-b966a70ffce343e2808a21e51b493e09
Source dataset
uspto-grants-1987_01
Patent number
US04634715

Reaction notes

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