反应详情

A solution of 10 gm (0.082 mol) of furfurylmethylamine in 50 ml of ethanol and 10 gm of triethylamine was mixed with 17 gm of p-methylphenacylbromide and stirred for two hours. The triethylamine hydrochloride precipitated was subjected to suction filtration. The mother liquor was mixed with 4 gm of sodium borohydride and stirred for one hour at ambient temperature. Then, water was added, and the mixture was extracted with ether. The ether solution was dried, and the ether was distilled off in vacuo. The 2-furfuryl-2-methylamino-1-p-methylphenyl ethanol was left behind in the form of an oil.

1. customThe triethylamine hydrochloride precipitated
2. filtrationwas subjected to suction filtration
3. additionThe mother liquor was mixed with 4 gm of sodium borohydride
4. stirringstirred for one hour at ambient temperature
5. additionThen, water was added
6. extractionthe mixture was extracted with ether
7. dry with materialThe ether solution was dried
8. distillationthe ether was distilled off in vacuo
9. waitThe 2-furfuryl-2-methylamino-1-p-methylphenyl ethanol was left behind in the form of an oil