Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 980313Generated: October 29, 2026

2-Vinylquinoline → 8-Fluoro-2,3,4,5-tetrahydro-2-[2-(2-quinolinyl)ethyl]-1H-pyrido[4-3-b]indole

https://huagongshe.com/reaction/980313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-VinylquinolineHCID 69875—
ReactantTetrafluoro-m-phenylenediamine dihydrochlorideHCID 149026—
Product8-Fluoro-2,3,4,5-tetrahydro-2-[2-(2-quinolinyl)ethyl]-1H-pyrido[4-3-b]indoleHCID 13772442—

Reaction Steps

The title compound was prepared following the procedure of Example 2 with the exception that 2-vinylquinoline was used instead of 2-vinylpyridine. The product was converted to the dihydrochloride salt; mp 192°-194° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04636563
Source datasetuspto-grants-1987_01
ORD IDord-8ba977ed4d1f4935be9f92a95f034f28
Source noteuspto-grants-1987_01