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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 980314Generated: October 30, 2026

2-Vinylpyridine → 2,3,4,5-Tetrahydro-2-[2-(2-quinolinyl)ethyl]-1H-pyrido[4,3-b]indole

https://huagongshe.com/reaction/980314

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-VinylpyridineHCID 7521—
Reactant2-VinylquinolineHCID 69875—
ReactantTetrafluoro-m-phenylenediamine dihydrochlorideHCID 149026—
Reactant1H,2H,3H,4H,5H-pyrido[4,3-b]indoleHCID 723230—
Product2,3,4,5-Tetrahydro-2-[2-(2-quinolinyl)ethyl]-1H-pyrido[4,3-b]indoleHCID 13772444—

Reaction Steps

The title compound was prepared following the procedure of Example 2 with the exception that 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole was used instead of 8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole and 2-vinylquinoline replaced 2-vinylpyridine. The product was converted to the dihydrochloride; mp 195°-197° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04636563
Source datasetuspto-grants-1987_01
ORD IDord-591407285cc342c8882fbf69f03755a0
Source noteuspto-grants-1987_01